The molecule NAD+ and its form NADP are part of the energy forming process. They are required for energy production and fat oxidation and the production of DNA and RNA precursors, lipids, and steroid hormones. It is also used in DNA repair and gene expression.
NAD+ precursors nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) can both be converted to NAD+, but NMN must first be converted to NR in order to enter the cells.
In a clinical trial, nicotinamide riboside was supplemented in three different doses -100mg per day, 300mg per day and 1000mg per day. Researchers found that at two weeks serum levels of NAD+ had increased 22% at 100mg, 51% at 300mg and 142% at 1000mg per day.
Scientific Reports. 2019.
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