Allergies are an immune response typically initiated by allergens from pollen or food resulting in mucus, itchy eyes, eczema and even digestive disturbances. The immune system may then form IgE antibodies to the allergen and attach to immune or mast cells that are found on respiratory and digestive tract surfaces.
This process sensitizes and primes the immune cells for the next allergen exposure and allergy response. When the allergens interact with the mast cells, they can begin to breakdown or degranulate and release symptom causing histamine in the process. Fermented foods, cured meats and older proteins contain or may release high levels of histamine.
Mast Cell Stabilization Molecules
Here are naturally occurring molecules with successful research results that showed to stabilize mast cells and limit the amount of histamine released.
- Quercetin in the EMIQ form stabilizes Mast Cells, inhibits histamine release and significantly reduced “itchy eye” allergy symptoms.
- Flavonoid Luteolin stabilized Mast Cells and reduced immune activation.
Quiet the Immune Response
- Nettle Leaf Extract reduced histamine release while inhibiting overall allergy immune and mast cell activity.
- Perilla Extract reduced activity in allergy forming Th2 antibody pathway, mast cells and longer lasting eosinophil allergy symptoms.
- Curcumin increased the immune cytokine IL-10 and IgA antibodies that suppress allergy.
- Resveratrol lowered inflammatory response to allergy reactions.
- Vitamin C has shown to reduce histamine.
Allergic Asthma
- N-Acetylcysteine supports antioxidant balance and limits respiratory inflammation.
- Vitamin A reduced respiratory and vascular inflammation as well as allergy and inflammatory promoting eosinophils
Food Histamine
Foods may contain histamine or cause the release of histamine resulting in both systemic and GI tract allergy response.
- Body Enzyme DAO breaks down food histamine in the GI.
- Probiotic Strains such as BB536, and L. Rhamnosus GG supported Mast Cell stabilization and increased histamine breakdown from food.
References: Central European Journal of Immunology. 2018 Dec 31; 43(4) European Review for Medical and Pharmacological Sciences. 2022 Jun; 26(12)
Phytotherapy Research. 2009 Jul; 23(7) Evidence-Based Complementary and Alternative Medicine. 2015 Apr 20 Critical Reviews in Food Science and Nutrition. 2019; 59(1)
World Allergy Organization Journal. 2020 Oct 22; 13(10) Nutrients. 2021 Sep 29; 13(10) Antioxidants. 2023; 12(9) Iranian Journal of Allergy, Asthma, and Immunology. 2021 Dec 8; 20(6)
Food Science and Biotechnology. 2019 May 24; 28(6) International Journal of Molecular Sciences. 2023 Feb 19; 24(4) Journal of the Science of Food and Agriculture. 2024 Jun 10
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
