A study investigated whether adding oat β-glucan (a type of soluble fiber) to the diet could help reduce the levels of PFAS (“forever chemicals”) in the body. PFAS are persistent environmental contaminants linked to negative health effects and tend to remain in the body because they’re recycled through the gut rather than eliminated.
The study compared the effects of oat β-glucan or another fiber (inulin) on 7 different types of PFAS. The group fed oat β-glucan showed trends toward lower serum PFAS levels compared to the inulin group.
Additionally, the oat β-glucan group had lower body fat relative to body weight and lower triglyceride concentrations in liver and intestine, and some changes in liver gene expression related to metabolism. Overall, this pilot work suggests that oat fiber might help reduce PFAS in the body as well as improve certain aspects of lipid metabolism.
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Reference: Toxicology and Applied Pharmacology. 2025
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