LDL, the so-called “bad” cholesterol, easily becomes more dangerous by losing an electron when it interacts with free radical molecules in the body. As the name suggests, free radicals are highly reactive and unstable molecules that are created in a process know as oxidation. Antioxidants have extra electrons that are donated to free radicals to neutralize them. When LDL becomes oxidized, damage can occur in the artery walls, and the process of atherosclerosis (cardiovascular disease) can begin. Unfortunately, LDL oxidizes easily. When an individual has high levels of LDL, it is expected that levels of oxidized LDL will be high as well. Components of the diet which raise LDL and oxidized LDL include saturated fats, trans fats, sugar, and excess starches.
LOX-1 – Oxidized LDL and Inhibitors
A major contributor to the formation and progression of atherosclerosis is a protein called LOX-1. It allows oxidized LDL to attach to the artery walls and for damage to occur.
For LOX-1, the goal is to reduce the amount present in the body, and these flavonoid molecules showed to lower levels:
- Epigallocatechin-3-gallate (EGCG) from green tea extract
- Punicalagins from pomegranate extract
- Quercetin EMIQ extract
- Apigenin from extract
- Procyanidins from tea and cocoa
The Body’s Protective PON1 Enzyme
The enzyme PON1 plays a protective role in reducing atherosclerosis risk in the arteries. It can prevent the oxidation of LDL from occurring in the first place.
For PON1, the goal is to increase the amount present in the body, and the following molecules have shown to boost PON1:
- Pomegranate extract
- Quercetin EMIQ extract
- Isorhamnetin from Quercetin EMIQ extract, Parsley, & Almonds
- Gamma Vitamin E & Tocorienols and Vitamin C
Additional Powerful Cardio Support
- Liposomal Glutathione reduced oxidation of LDL cholesterol by 17% and improved atherosclerotic lesions by 30%.
- Citrus Bergamot extract study results showed an LDL cholesterol reduction of 33% and HDL increase of 13.6%.
- 12mg of the Carotenoid Astaxanthin significantly increased HDL cholesterol.
- Cardio risk factor Homocysteine is metabolized by methyl B12 and Folate in the body. Supplemental B12 and Folate resulted in a 31.9% reduction of Homocysteine in 30 days.
References available upon request. These statements have not been evaluated by the Food and Drug Administration. Research, nutritional information, and products are not intended to diagnose, treat, cure or prevent any disease. Consult your physician before initiating any new dietary or supplement program.
