L-ergothioneine is a deaging molecule which is most prevalent in mushrooms. Researchers have found many beneficial properties of L-ergothioneine that show it to contribute to longevity.
Antioxidant and cell protection properties
- Ability to break down damaging free radicals and protect against their formation
- Maintains cellular reduced glutathione levels
- Neutralizes dangerous metals in the body
Anti-aging properties
- Showed to decrease the rate of chromosome telomere shortening-a marker of aging
- Decreased cell nucleus and mitochondrial DNA damage
- Decreased risk of chronic diseases of aging
- Ability to protect heart, brain, and other organs
Neuroprotective Properties
- Ability to cross the blood-brain barrier
- Lower levels of ergothioneine intake were found in people with mild cognitive impairment and Parkinson’s Disease
- Improves stress-related sleep disorders and relieves depressive like behaviors
Journal of Nutritional Science 2020, Frontiers in Pharmacology 2022